fragging devils hand while still in the tank

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I searched& didn't really find any solid answers to my question
I have a large devils hand that needs to be trimmed back
Anyone know for sure if I can frag it while still in the tank? It's attached to a large rock that is not removable
I'll run carbon obviously , but not sure on how toxic it is
My tank is 220 gal
Thanks
Robert
 
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